Polyarteritis nodosa is an inflammation of the blood vessels that typically results in blocking of blood flow to organs. The kidneys, skin, joints, muscles, peripheral nerves, and GI tract are most commonly affected, but any organ can be. The kidneys, skin, joints, muscles, peripheral nerves, and GI tract are most commonly affected, but any organ can be.
Patients typically present with systemic symptoms (eg, fever, fatigue). Mostly commonly affected are the kidneys, skin, peripheral nerves, joints, muscles, and GI tract. Often affected are the liver, heart, and kidneys.
PAN may develop slowly, over several weeks or months. Patients may have non-specific complaints such as fever, malaise, weight loss, anorexia, and abdominal pain. Polyarteritis Nodosa results in the following complications:
- Brain Damage – Central nervous system (CNS) lesions may occur 2 to 3 years after the onset of PAN and may lead to cognitive dysfunction, decreased alertness, seizures and neurologic deficits.
- Heart Attack or Congestive Heart Failure
- Intense Stomach Pain
- Kidney Damage
- Muscle Pain
- Allergic Reaction/Anaphylaxis
- Autoimmune Disorders
- Blood Clots
- Blood Disorders
- Bowel Injury
- Brain Damage
- Chronic Fatigue
- Nerve Damage
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